DRUG-INDUCED MOVEMENT DISORDERS
Identifieur interne : 000432 ( Main/Exploration ); précédent : 000431; suivant : 000433DRUG-INDUCED MOVEMENT DISORDERS
Auteurs : Nico J. Diederich [États-Unis, Luxembourg (pays)] ; Christopher G. Goetz [États-Unis]Source :
- Neurologic Clinics [ 0733-8619 ] ; 1998.
Abstract
Although known for four decades,33,105 drug-induced movement disorders are still underrecognized. Patients are thought to suffer from idiopathic Parkinson's disease (PD), when, in fact, they have drug-induced parkinsonism (DIP) often from unidentified neuroleptics given for vegetative or psychiatric symptoms. Neuroleptics, drugs that are dopamine receptor blockers (DRBs), can cause a gamut of movement disorders occurring acutely, subacutely, and chronically. The movement disorderinducing potential of new drugs is often not recognized until they have been marketed and large populations have been exposed. This article focuses on several movement disorders caused by various commonly prescribed drugs but does not include neuroleptic malignant syndrome or rare chronic stereotypies. Classic theories as well as new pathophysiologic concepts are discussed.
Url:
DOI: 10.1016/S0733-8619(05)70370-4
Affiliations:
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Le document en format XML
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<front><div type="abstract">Although known for four decades,33,105 drug-induced movement disorders are still underrecognized. Patients are thought to suffer from idiopathic Parkinson's disease (PD), when, in fact, they have drug-induced parkinsonism (DIP) often from unidentified neuroleptics given for vegetative or psychiatric symptoms. Neuroleptics, drugs that are dopamine receptor blockers (DRBs), can cause a gamut of movement disorders occurring acutely, subacutely, and chronically. The movement disorderinducing potential of new drugs is often not recognized until they have been marketed and large populations have been exposed. This article focuses on several movement disorders caused by various commonly prescribed drugs but does not include neuroleptic malignant syndrome or rare chronic stereotypies. Classic theories as well as new pathophysiologic concepts are discussed.</div>
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